I tried Pain Quench on arthritic bone. As soon as I applied it I felt a slight cooling sensation, which was calming and let me know the medicine was working. That bone did not hurt or bother me for the rest of the night. Using what was still left over from rubbing it into my arthritic bone, I applied the rest to a cat scratch that I had on my hand. The next day the cat scratch was almost healed, which was originally 2 inches long. I will definitely be purchasing more Pain Quench from BAK 2 Basics, not only for pain but to help heal any cuts or scratches.